Medical & Clinical Reviews

Neuropsychiatric Lupus-Review and New Models for Its Classification and Diagnostic Approach

The objective of the study is to review current concepts about neuropsychiatric lupus, emphasizing new proposals for its diagnostic approach. An advanced search was carried out in the PubMed database to finally include and make an exhaustive review of 59 articles. The manifestations of Neuropsychiatric Lupus (NPSLE) have been described in a wide way and in a wide spectrum; at present it is known that some associations made previously do not actually have to do directly with the pathogenesis of Systemic Lupus Erythematosus (SLE), on the other hand we make a contribution in the review of the literature that we consider essential for clinicians, since have described new models and algorithms to objectively establish whether or not a patient has PNLL, advances have also been described in the discovery of new biomarkers and imaging techniques, especially nuclear magnetic resonance imaging, which can be decisive in the management and prognosis of patients affected by this sometimes forgotten entity.

Author(s): Sebastian Camilo Duque Palacios* and Maria de Los Angeles Araque Coronado

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