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Genetics plays an influence in all diseases, to a greater or lesser level. Disease processes are influenced by variations in our DNA and variances in how that DNA operates (alone or in combination), as well as the environment (which includes our lifestyle). This overview looks at the genetic foundation of human disease, including single gene disorders, chromosomal abnormalities, epigenetics, cancer, and complex disorders, and how current knowledge and technology developments can be used to provide patients with proper diagnosis, management, and therapy.

Alan Dubro

Abstract | PDF

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